*Seminar Series: SCMB Seminar
*Location: AIBN Seminar Room
*Date: 19/07/2017
*Time: 12:00

Speaker #1 details
*Title of talk: Seminal fluid - new and unexpected roles in reproduction and epigenetic programming
*Speaker's name: Professor Sarah Robertson
*Speaker's organisation: Robinson Research Institute, School of Paediatrics & Reproductive Health, The University of Adelaide
Speaker's city/state/country: Sa
Talk Abstract: In mammalian reproduction, seminal fluid is often viewed solely as the vehicle for delivery of sperm to fertilise oocytes. But the male contribution is not so simple. In mouse and human systems we explore how signalling agents present in sperm and seminal plasma interact with the female reproductive tract after coitus, mediated by cytokines and microRNAs to modify the female immune response and receptivity for pregnancy, and impact survival and development in pre-implantation embryos. Our findings reveal a potent influence of seminal fluid composition on the conception environment with consequences for fertility and female reproductive investment, as well as epigenetic mechanisms of developmental programming in offspring.
Speaker's bio: Professor Sarah Robertson is Director of the University of Adelaide's Robinson Research Institute and Head of the Reproductive Immunology research group. She is known internationally for innovative research in reproductive immunology that has formed the basis for a new understanding of the origins of health at conception. Her work shows that the immune system channels environmental signals from both female and male parents to contribute to reproductive success and shape offspring phenotype through non-genomic pathways. These discoveries are improving practise in reproductive medicine and providing insight into early life origins of child health. Her work is funded by the NHMRC, the Australian Research Council, the Canadian Institutes of Health Research and the Global Alliance for Prevention of Prematurity and Stillbirth / Gates Foundation.

Speaker #2 details
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Other Details: If you would like to meet with the speaker, please contact Marloes Dekker (m.dekker@uq.edu.au)
*Host name: Marloes Dekker Nitert
Host phone number:
*Host email: m.dekker@uq.edu.au