*Seminar Series: QIMR Lecture
*Location: QIMR Herston - Bancroft Auditorium -Level 6
*Date: 06/06/2017
*Time: 13:00

Speaker #1 details
*Title of talk: Cancer Biology to Nanomedicine-Based Therapeutics
*Speaker's name: Professor Maria Kavallaris
*Speaker's organisation: UNSW
Speaker's city/state/country: NSW
Talk Abstract: Cancer remains a significant clinical problem and is a major cause of morbidity and mortality in society. Development of resistance to therapy is a major clinical challenge and elucidating the mechanisms that underlie drug resistance is essential if we are to develop solutions and new more effective therapies. The propensity of solid tumours to metastasise to distant organs poses a major barrier to cure, since metastatic cancer cells are often refractory to therapy. Recent studies from our laboratory have revealed key roles for specific microtubule proteins in cell survival signalling pathways. Given the challenges in targeting these proteins with small molecule agents, we have been developing nanoparticles to deliver siRNA/miRNA and chemotherapeutic drugs to overcome resistance and reduce the toxic side effects of conventional chemotherapy.
Speaker's bio: Professor Kavallaris's research contributions include identifying the mechanisms of action and resistance to anticancer drugs, discovering new protein interactions in cancer and development of less toxic cancer therapies using nanotechnology. She has held numerous competitive fellowships, including a Principal Research Fellowship from NHMRC and from the AAHMS. Her work has been recognised by numerous awards/prizes including an AACR Women in Cancer Research Award, Young Tall Poppy Award and Australian Museum Eureka Prize. She was also selected for The Australian Financial Review and Westpac 100 Women of Influence Award 2015 and the Knowledge Nation 100 innovation leaders.

Speaker #2 details
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Other Details:
*Host name: Nancy Cloake
Host phone number: 1800993000
*Host email: nancy.cloake@qimrberghofer.edu.au