*Seminar Series: IMB Seminar Series
*Location: QBP Auditorium, Bld 80
*Date: 16/06/2017
*Time: 12:30

Speaker #1 details
*Title of talk: Predicting the future and reconstructing the past through protein engineering
*Speaker's name: Associate Professor Colin Jackson
*Speaker's organisation: Australian National University
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Talk Abstract: In this talk I will discuss some recent results from our laboratory in which we have used a variety of protein engineering approaches (loop design, ancestral reconstruction, directed evolution, combinatorial mutagenesis) to answer questions such as: How will TB evolve resistance to next-gen antibiotics? How will pesticide resistance develop? How can enzymes evolve novel functions? And how can enzymatic activity emerge from a non-catalytic binding protein scaffold?
Speaker's bio: Colin Jackson established a protein structure and engineering laboratory at the Research School of Chemistry in 2011/2012, after completing a Marie Curie Fellowship at the Institut de Biologie Structurale in Grenoble, France. His interests include functional annotation of proteins, bioinformatics, protein crystallography, computational structural biology, inhibitor design, protein engineering, enzyme catalysis, binding proteins and protein engineering. He works on medically-related proteins from humans and pathogens (TB/malaria), insect carboxylesterases, and xenobiotic-degrading enzymes.

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Other Details:
*Host name: Assocate Professor Brett Collins
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*Host email: imbevents@uq.edu.au