*Seminar Series: SCMB Molecular Bioscience
*Location: AIBN Seminar Room (Bldg 75)
*Date: 03/05/2017
*Time: 12:00

Speaker #1 details
*Title of talk: The Buffalo Genome and Applications
*Speaker's name: Prof John Williams
*Speaker's organisation: The University of Adelaide
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Talk Abstract: Water buffalo (Bubalus bubalis) was domesticated about 5000 years ago, and since then it has been of economic importance in most regions of the world. There were no genomic resources available for buffalo and so we created a 90K SNP chip which we used to assess the global genetic diversity of both river and swamp buffalo and to identify loci putatively involved in milk production using a genome-wide association study. A reference genome sequence is important for understanding the biology of a species, managing genetic diversity and, in the case of domestic animals, to apply new genome-based selection methods for genetic improvement. I will describe how we created a draft di novo genome sequence assembly for the buffalo using short sequence reads, and annotated this genome to identify genes. More recently we have been using the latest long sequence read technology and genome assembly tools to create a chromosome level assembly. I will also describe how, using genome sequencing approaches to compare affected and normal buffalo we were able to identify the likely mutation responsible for a serious heritable defect affecting river buffalo in Italy with a view to creating a test to eradicate the mutation from the population.
Speaker's bio: Prof Williams obtained his PhD in Biochemistry (1983) from the National Institute for Medical Research, London. He then moved to Edinburgh in Scotland to start his work on genetics, first with the University of Edinburgh on Drosophila before moving into the field of agriculture at the Roslin Institute, where he was Head of the Bovine Genomics Section, and Coordinator of the Institute Complex Traits Programme until 2005. He moved to the Parco Tecnologico Padano in Italy (2005) where he was the Science Director overseeing research on livestock and crop species until 2015. He was appointed to the JS Davies Research Chair in the School of Animal and Veterinary Sciences at the University of Adelaide in Australia (2015). Prof Williams' research has focussed on the genetic improvement of animals and has had 8 European Union funded projects on topics including dairy production, meat quality, cattle health, BSE and basic genetics/genomics research. In Adelaide he is the director of the Davies Research Centre, working on ruminants with a particular focus on sheep and beef cattle but with an ongoing interest in buffalo.

Speaker #2 details
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Other Details:
*Host name: Marina Fortes
Host phone number:
*Host email: m.fortes@uq.edu.au