*Seminar Series: IMB Chemistry and Structural Biology Division Seminar
*Location: Seminar Room 3.142, QBP, UQ St Lucia
*Date: 13/04/2017
*Time: 12:30

Speaker #1 details
*Title of talk: Probing the functional complexity of ancient oxytocin in health and disease
*Speaker's name: Dr Markus Muttenthaler
*Speaker's organisation: UQ IMB
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Talk Abstract: The oxytocin and vasopressin signalling system goes back 600 million years, is highly conserved and regulates many important central and peripheral functions. Here I will discuss the challenges and therapeutic potential of this signalling system. I will describe the chemical strategies that we used to overcome species selectivity differences and the development of the first bivalent oxytocin receptor superagonist with a 1,000-fold potency improvement.
Speaker's bio: Markus Muttenthaler is a biological and medicinal chemist with interests in neuropeptide research and the translation of nature's diversity to develop molecular probes, diagnostics and therapeutics.

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Other Details:
*Host name: Prof Paul Alewood
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*Host email: p.alewood@imb.uq.edu.au