*Seminar Series: SCMB Chemistry Seminars
*Location: AIBN Seminar Room (Bldg 75)
*Date: 10/04/2017
*Time: 12:00

Speaker #1 details
*Title of talk: Transactions of NS3 and NS5 in Dengue viral RNA replication
*Speaker's name: Professor Subhash Vasudevan
*Speaker's organisation: Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore
Speaker's city/state/country: Singapore
Website:
Talk Abstract: Dengue virus (DENV) replication requires RNA-RNA, RNA-protein and protein-protein interactions to carry out viral RNA synthesis. In order to have a better understanding of the critical interactions involved in the process we have used structural biology, biochemical and reverse genetics studies to tease out some of the mechanisms involved in the interactions between DENV multifunctional non-structural proteins NS3 and NS5. The possibility that some of the interactions can form ideal targets for antiviral drug discovery will be discussed in the context of RNA binding specificities in NS3.

Subhash Vasudevan is a Professor and Principal Investigator in the Signature Program for Emerging Infectious Diseases at Duke-National University of Singapore Graduate Medical School. He obtained his PhD at The Australian National University (ANU) in 1989 and post-doctoral training at the Max-Planck Institute for Biophysics and Research School of Chemistry@ANU. His major research interest is in the area of antiviral drug discovery against dengue and related viruses.
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Speaker #2 details
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Other Details:
*Host name: Kate Stacey
Host phone number:
*Host email: katryn.stacey@uq.edu.au