*Seminar Series: IMB Chemistry and Structural Biology Seminar
*Location: Seminar Room 3.142
*Date: 06/04/2017
*Time: 12:30

Speaker #1 details
*Title of talk: Stabilising reactive bacterial heterocycles that activate T cells
*Speaker's name: Dr Jeff Mak
*Speaker's organisation: IMB
Speaker's city/state/country:
Talk Abstract: Mucosal associated invariant T (MAIT) cells are T lymphocytes important in antibacterial defence. They are activated by unstable heterocycles derived from the bacterial biosynthesis of riboflavin (vitamin B2). I will describe our rationally designed kinetically controlled synthesis of the antigens, and computer assisted creation of a stable and functionally equivalent analogue.
Speaker's bio: Jeffrey Mak (PhD, advisor: Prof. Craig Williams, SCMB) joined the Fairlie group in 2012 to undertake research at the chemistry/biology interface.

Speaker #2 details
*Title of talk: Assassin bugs inject anatomically separable predatory and defensive venoms
*Speaker's name: Dr Andrew Walker
*Speaker's organisation: IMB
Speaker's city/state/country:
Talk Abstract: Assassin bugs (Insecta: Reduviidae) have anatomically complex venom glands, and use venom variously for prey capture, defense and extra-oral digestion. In this talk I will describe how the reduviid venom system is exquisitely adapted to allow the injection of two different multicomponent venoms that accumulate in two separate gland lumens.
Speaker's bio: Andrew is a postdoctoral researcher in the King laboratory interested in arthropod venom and silk proteins.

Other Details:
*Host name: Prof David Fairlie
Host phone number:
*Host email: d.fairlie@imb.uq.edu.au